The game continues shortly after the events of Assassin's Creed, where, in 2012, Desmond Miles (Nolan North) is still a prisoner at Abstergo Industries after searching the memories of his ancestor, the Assassin, Altaïr, in the Animus. Abstergo, the modern-day Knights Templar, had been using Desmond to locate powerful out-of-place artifacts called "Pieces of Eden." Using the "Eagle Vision" ability he gained as a result of the "bleeding effect" (from overexposure to the Animus), Desmond is able to see messages and symbols written in blood on his bedroom wall, written by the former test subject, named "Subject 16 (Cam Clarke)". Lucy Stillman (Kristen Bell), a former researcher for Abstergo and an Assassin, frees Desmond and brings him to a secret hideout used by herself and two other Assassins, historian Shaun Hastings (Danny Wallace) and computer expert Rebecca Crane (Eliza Schneider). With their own version of the Animus, dubbed the 'Animus 2.0', they invite Desmond to help them discover the memories of his ancestor, Ezio Auditore da Firenze, for two reasons: to train Desmond in Assassin skills through the bleeding effect, and to find other Pieces of Eden.